Angel V Peterchev

Associate Professor in Psychiatry and Behavioral Sciences
Associate Professor in Psychiatry and Behavioral Sciences
Associate Professor in Psychiatry and Behavioral Sciences
Assistant Professor in the Department of Electrical and Computer Engineering
Associate Professor in the Department of Electrical and Computer Engineering
Assistant Professor of Biomedical Engineering
Associate Professor in the Department of Electrical and Computer Engineering
Associate Professor in Neurosurgery
Associate Professor in the Department of Electrical and Computer Engineering
Associate Professor in Neurosurgery

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I direct the Brain Stimulation Engineering Lab (BSEL) which focuses on the development, modeling, and application of devices and paradigms for transcranial brain stimulation. Transcranial brain stimulation involves non-invasive delivery of fields (e.g., electric and magnetic) to the brain that modulate neural activity. It is widely used as a tool for research and a therapeutic intervention in neurology and psychiatry, including several FDA-cleared indications. BSEL develops novel technology such as devices for transcranial magnetic stimulation (TMS) that leverage design techniques from power electronics and computational electromagnetics to enable more flexible stimulus control, focal stimulation, and quiet operation. We also deploy these devices in experimental studies to characterize and optimize the brain response to TMS. Another line of work is multi-scale computational models that couple simulations of the electromagnetic fields, single neuron responses, and neural population modulation induced by electric and magnetic brain stimulation. These models are calibrated and validated with experimental neural recordings through various collaborations. Apart from understanding of mechanisms, we develop modeling, algorithmic, and targeting tools for response estimation, dose individualization, and precise localization of transcranial brain stimulation using advanced techniques such as artificial neural networks and machine learning. Moreover, BSEL is involved in the integration of transcranial brain stimulation with robotics, neuronavigation, intracranial electrophysiology recordings, and imaging modalities such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), as well as the evaluation of the safety of device–device interactions, for example between transcranial stimulators and implants. Importantly, we collaborate widely with neuroscientists and clinicians within Duke and at other institutions to translate developments from the lab to research and clinical applications. For over 15 years, BSEL has been continuously supported with multiple NIH grants as well as funding by DARPA, NSF, Brain & Behavior Research Foundation, Coulter Foundation, Duke Institute for Brain Sciences, MEDx, Duke University Energy Initiative, and industry. Further, some of our technology has been commercialized, for example as ElevateTMS cTMS, or incorporated in free software packages, such as SimNIBS.

Education

  • Ph.D., University of California - Berkeley (2005)
  • Ph.D., University of California at Berkeley (2005)
  • M.S., University of California - Berkeley (2002)
  • B.A., Harvard University (1999)

Mailing Address

Nicholas Institute for Energy, Environment & Sustainability
Box 90467
Durham, NC 27708

Street / Delivery Address

Nicholas Institute for Energy, Environment & Sustainability
140 Science Drive
Gross Hall, Suite 101
Durham, NC 27708

919-613-1305 

Sep
29
Location: Page Auditorium, 402 Chapel Drive
Time: 4:00 pm to 5:30 pm
Sep
30
Location: Field Auditorium, Grainger Hall, Circuit Drive
Time: 10:00 am to 11:00 am
Sep
30
Location: Duke Ahmadieh Family Auditorium (Gross Hall) + Livestream
Time: 12:00 pm to 1:15 pm