Donald Patrick McDonnell

Core Faculty in Innovation & Entrepreneurship

Pages

The research in our group is focused on the development and application of mechanism based approaches to identify novel therapeutics for use in the treatment and prevention of hormonally responsive cancers. Specifically we are interested in the pharmaceutical exploitation of the estrogen and androgen receptors as therapeutic targets in breast and prostate cancers and in defining how these receptors influence the pathogenesis of these diseases. These efforts have led to the discovery of several drugs that are currently being evaluated in the clinic as cancer therapeutics, and to the identification of potential biomarkers and predictors of response that can help to target the use of these new drugs. Most recently we have explored approaches to treat triple negative breast cancer and have identified an important pathway that links obesity/dyslipidemia and cancer risk.

Publications

Mailing Address

Nicholas Institute for Energy, Environment & Sustainability
Box 90467
Durham, NC 27708

Street / Delivery Address

Nicholas Institute for Energy, Environment & Sustainability
140 Science Drive
Gross Hall, Suite 101
Durham, NC 27708

919-613-1305 

Sep
29
Location: Page Auditorium, 402 Chapel Drive
Time: 4:00 pm to 5:30 pm
Sep
30
Location: Field Auditorium, Grainger Hall, Circuit Drive
Time: 10:00 am to 11:00 am
Sep
30
Location: Duke Ahmadieh Family Auditorium (Gross Hall) + Livestream
Time: 12:00 pm to 1:15 pm