Mathew, Joseph P.
(919) 681-6646
mathe014@mc.duke.edu
2301 Erwin Road, 5692 Hafs Building
Durham, NC 27710
Box 3094 Med Ctr
Durham, NC 27710

Joseph P. Mathew

Jerry Reves, M.D. Distinguished Professor of Cardiac Anesthesiology
Jerry Reves, M.D. Professor of Cardiac Anesthesiology
Professor of Anesthesiology
Professor of Anesthesiology
Chair of Anesthesiology
Core Faculty in Innovation & Entrepreneurship
Core Faculty in Innovation & Entrepreneurship
Current research interests include:
1. The relationship between white matter patency, functional connectivity (fMRI) and neurocognitive function following cardiac surgery.
2. The relationship between global and regional cortical beta-amyloid deposition and postoperative cognitive decline.
3. The effect of lidocaine infusion upon neurocognitive function following cardiac surgery.
4. The association between genotype and outcome after cardiac surgery.
5. Atrial fibrillation following cardiopulmonary bypass.

Education

  • M.B.A., University of Massachusetts at Amherst (2013)
  • M.B.A., University of Massachusetts - Amherst (2013)
  • M.H.S., Duke University School of Medicine (2008)
  • Other, Yale University (1998)
  • Other, Yale University (1991)
  • Other, Yale University (1990)
  • M.D., University of Texas at Dallas (1986)

Publications

Blood-brain barrier permeability and cognitive dysfunction after surgery - A pilot study. (06/2023)
A Role for Blood-brain Barrier Dysfunction in Delirium following Non-Cardiac Surgery in Older adults. (05/2023)
Corrigendum to 'Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study' (Br J Anaesth 2021; 127: 917-928). (05/2023)
Utilization and Outcomes of Extracorporeal Membrane Oxygenation Following Traumatic Brain Injury in the United States. (05/2023)
Neuromodulation therapy for atrial fibrillation. (01/2023)
Early Vasopressor Utilization Strategies and Outcomes in Critically Ill Patients With Severe Traumatic Brain Injury. (12/2022)
Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling. (12/2022)
Identification of Trajectory-Based Acute Kidney Injury Phenotypes Among Cardiac Surgery Patients. (12/2022)
The potential link between obstructive sleep apnea and postoperative neurocognitive disorders: current knowledge and possible mechanisms. (10/2022)
Risk Factors and Neurological Outcomes Associated With Circulatory Shock After Moderate-Severe Traumatic Brain Injury: A TRACK-TBI Study. (09/2022)

Mailing Address

Nicholas Institute for Energy, Environment & Sustainability
Box 90467
Durham, NC 27708

Street / Delivery Address

Nicholas Institute for Energy, Environment & Sustainability
140 Science Drive
Gross Hall, Suite 101
Durham, NC 27708

919-613-1305